Description

Difluoroacetate is a versatile organofluorine building block and reagent, identified by CAS NO 1208249-85-7. This compound is valued for its ability to introduce the difluoroacetate moiety, a key functional group that can modulate the physicochemical and metabolic properties of target molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides.
• Material Science: Serves as a precursor for fluorinated polymers, coatings, and specialty materials with unique surface properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and esterification reactions to incorporate the difluoroacetyl group.
• Life Science Research: Utilized as a biochemical tool and probe in medicinal chemistry and drug discovery programs.
• Fluorine Chemistry: A fundamental reagent for exploring new methodologies in organofluorine chemistry.

Basic Information

Item	Details
Product Name	Difluoroacetate
CAS No.	1208249-85-7
Molecular Formula	C2HF2O2 (for difluoroacetic acid, typical parent form; salt/ester forms vary)
Molecular Weight	96.03 g/mol (for difluoroacetic acid)
Synonyms	Difluoroacetic acid derivative; 2,2-Difluoroacetate; DFA salt; DFA ester; Difluoroethanoate; Acetate, 2,2-difluoro-; Potassium difluoroacetate (common salt form); Sodium difluoroacetate (common salt form); Methyl difluoroacetate (common ester form); Ethyl difluoroacetate (common ester form)
EINECS	Contact for details

Quality Control

Our Difluoroacetate products undergo rigorous quality testing to ensure compliance with industry standards and customer-specific requirements. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports production under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.