Description

(4-Fluoro-Phenyl)-Morpholin-4-Yl-Acetonitrile is a high-purity, versatile nitrile-based building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a fluorinated aromatic ring and a morpholine moiety, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl and morpholine groups.
• Chemical Synthesis Reagent: Serves as a versatile precursor for further functionalization via the reactive nitrile group, enabling access to amides, acids, and heterocycles.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	(4-Fluoro-Phenyl)-Morpholin-4-Yl-Acetonitrile
CAS No.	1208081-30-4
Molecular Formula	C₁₂H₁₃FN₂O
Molecular Weight	220.24 g/mol
Synonyms	4-Fluorophenyl(morpholino)acetonitrile; 2-(4-Fluorophenyl)-2-morpholinoacetonitrile; (4-Fluorophenyl)(morpholino)acetonitrile; 4-Fluoro-α-morpholinobenzeneacetonitrile; 2-Morpholino-2-(4-fluorophenyl)acetonitrile; α-Morpholino-4-fluorophenylacetonitrile; 1208081-30-4
EINECS	Contact for details

Quality Control

Our (4-Fluoro-Phenyl)-Morpholin-4-Yl-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.