Description

1-Bromo-5-Fluoro-2,4-Dimethoxybenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine and bromine atoms for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic core.
• Fluorinated Compound Library: An essential building block for combinatorial chemistry and the generation of diverse fluorinated compound libraries for screening.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the custom synthesis of proprietary compounds and complex molecules under cGMP conditions.

Basic Information

Item	Detail
Product Name	1-Bromo-5-Fluoro-2,4-Dimethoxybenzene
CAS No.	1208077-05-7
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	2,4-Dimethoxy-1-bromo-5-fluorobenzene; 5-Fluoro-1-bromo-2,4-dimethoxybenzene; 1-Bromo-5-fluoro-2,4-dimethoxybenzene; 2-Bromo-4-fluoro-1,5-dimethoxybenzene; Benzene, 1-bromo-5-fluoro-2,4-dimethoxy-; 1208077-05-7 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-5-Fluoro-2,4-Dimethoxybenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.