Description

1-(2-Trifluoromethylphenyl)-1H-Imidazole-2-Carboxylic Acid Lithium Salt is a high-purity, organometallic salt derivative of a functionalized imidazole, designed for advanced chemical synthesis and pharmaceutical research. This compound is valued for its role as a key synthetic intermediate or ligand in the development of active pharmaceutical ingredients (APIs) and specialty chemicals. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Ligand in Catalysis: Used as a specialized ligand in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to facilitate challenging bond formations.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides or fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Investigated for incorporation into organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated imidazole core and lithium ion.
• Chemical Synthesis: Employed in academic and industrial R&D for the preparation of complex heterocyclic compounds and fine chemicals.

Basic Information

Product Name	1-(2-Trifluoromethylphenyl)-1H-Imidazole-2-Carboxylic Acid Lithium Salt
CAS No.	1208074-93-4
Molecular Formula	C11H6F3LiN2O2
Molecular Weight	262.11 g/mol (Lithium salt form)
Synonyms	Lithium 1-[2-(trifluoromethyl)phenyl]-1H-imidazole-2-carboxylate; 1-(2-Trifluoromethylphenyl)-1H-imidazole-2-carboxylic acid lithium salt; 1-(α,α,α-Trifluoro-o-tolyl)imidazole-2-carboxylic acid lithium salt; 2-Carboxy-1-(2-trifluoromethylphenyl)imidazole lithium salt; Lithium 1-(2-trifluoromethylphenyl)imidazole-2-carboxylate; TFMP-Imidazole-COOLi; 1208074-93-4
EINECS	Contact for details

Quality Control

Our production of 1-(2-Trifluoromethylphenyl)-1H-Imidazole-2-Carboxylic Acid Lithium Salt adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can tailor quality systems to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.