Description

Fluvastatin 3-Hydroxy-4,6-Diene is a key pharmaceutical intermediate in the synthesis of Fluvastatin, a widely prescribed statin medication. This compound is critical for ensuring the purity, efficacy, and safety of the final active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical and fine chemical industries engaged in the production of cholesterol-lowering drugs.

Application

• Primary Intermediate for the synthesis of Fluvastatin Sodium, the active ingredient in cholesterol-lowering medications.
• Research & Development of new statin analogs and related cardiovascular therapeutics in pharmaceutical laboratories.
• Process Chemistry for scale-up and optimization of Fluvastatin API manufacturing processes.
• Reference Standard for quality control and analytical method development in pharmaceutical QC/QA departments.
• Fine Chemical Synthesis for creating specialized derivatives for biological activity studies.

Basic Information

Product Name	Fluvastatin 3-Hydroxy-4,6-Diene
CAS No.	1207963-21-0
Molecular Formula	C24H25FNO4
Molecular Weight	410.46 g/mol
Synonyms	3-Hydroxy-4,6-diene Fluvastatin; (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhepta-4,6-dienoic Acid; Fluvastatin Dihydroxy Diene Intermediate; Lescol Intermediate; XU 62-320 Diene; Fluvastatin Diene; 4,6-Diene Fluvastatin
EINECS	Contact for details

Quality Control

Our Fluvastatin 3-Hydroxy-4,6-Diene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.