Description

1-Pyrrolidinecarboxylic Acid, 4-Amino-2-(Difluoromethyl)-, 1,1-D is a high-value, fluorinated pyrrolidine derivative serving as a sophisticated building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates both amino and difluoromethyl functional groups on the pyrrolidine ring, enabling precise modulation of physicochemical properties in target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Design: Employed in the development of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers and functional materials with tailored properties.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 4-Amino-2-(Difluoromethyl)-, 1,1-D
CAS No.	1207852-96-7
Molecular Formula	C7H10F2N2O2
Molecular Weight	192.16 g/mol
Synonyms	4-Amino-2-(difluoromethyl)-1-pyrrolidinecarboxylic acid; 2-(Difluoromethyl)-4-aminopyrrolidine-1-carboxylic acid; 4-Amino-2-(difluoromethyl)pyrrolidine-1-carboxylic acid; 1-Carboxy-4-amino-2-(difluoromethyl)pyrrolidine; (4-Amino-2-(difluoromethyl)pyrrolidin-1-yl)methanone; 1,1-D (common abbreviation); Fluorinated Proline Derivative; Amino-difluoromethyl pyrrolidine carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 4-Amino-2-(Difluoromethyl)-, 1,1-D is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend maintaining the product at 2-8°C under an inert atmosphere to preserve stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.