Description

n-(But-3-Ynyl)Methanesulfonamide is a specialized organic building block featuring a terminal alkyne functional group, making it a valuable intermediate for advanced synthesis. Its core value lies in enabling efficient, modular construction of complex molecules through click chemistry and other alkyne-based coupling reactions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for constructing targeted molecular scaffolds.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer modification, and material surface functionalization.
• Agrochemical Synthesis: Employed in the research and production of novel pesticides and herbicides, where the alkyne moiety allows for structural diversification.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with tailored properties.
• Chemical Biology Probes: Used to create labeled molecules for studying biological processes and target engagement.
• Ligand and Catalyst Development: Provides a handle for attaching complex molecules to metal centers or solid supports.

Basic Information

Item	Detail
Product Name	n-(But-3-Ynyl)Methanesulfonamide
CAS No.	1207840-15-0
Molecular Formula	C5H9NO2S
Molecular Weight	147.20 g/mol
Synonyms	N-(But-3-yn-1-yl)methanesulfonamide; Methanesulfonamide, N-3-butynyl-; But-3-yn-1-ylmethanesulfonamide; 3-Butynylmethanesulfonamide; N-(3-Butynyl)methanesulfonamide; 1207840-15-0; But-3-ynyl methanesulfonamide
EINECS	Contact for details

Quality Control

Our n-(But-3-Ynyl)Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.