Description

4-Fluoro-2-Methoxy-5-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	4-Fluoro-2-Methoxy-5-Methylphenylboronic Acid
CAS No.	1207428-92-9
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(4-Fluoro-2-methoxy-5-methylphenyl)boronic acid; 5-Methyl-4-fluoro-2-methoxybenzeneboronic acid; 2-Methoxy-5-methyl-4-fluorophenylboronic acid; 4-Fluoro-2-methoxy-5-methylbenzeneboronic acid; Boronic acid, B-(4-fluoro-2-methoxy-5-methylphenyl)-; 1207428-92-9; 4-Fluoro-5-methyl-2-methoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxy-5-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.