Description

1,1,1-Trifluoro-3-(Furan-2-Yl)Propan-2-Amine is a high-value fluorinated amine building block featuring a furan heterocycle, offering unique reactivity and physicochemical properties for advanced synthesis. This compound is critical for medicinal chemistry and agrochemical research, where its trifluoromethyl and amine groups serve as key pharmacophores to modulate bioactivity, lipophilicity, and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and antiviral drug candidates.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced efficacy and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis due to its amine functionality and stereogenic center.
• Material Science: Incorporated into monomers or additives for specialty polymers, coatings, and electronic materials to impart specific surface or bulk properties.
• Fluorine Chemistry Library: An essential component for building diverse screening libraries in drug discovery and chemical biology.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the commercial production of fluorinated fine chemicals.

Basic Information

Product Name	1,1,1-Trifluoro-3-(Furan-2-Yl)Propan-2-Amine
CAS No.	1207175-61-8
Molecular Formula	C7H8F3NO
Molecular Weight	179.14 g/mol
Synonyms	2-Amino-1,1,1-trifluoro-3-(2-furyl)propane; 3-(2-Furanyl)-1,1,1-trifluoro-2-propanamine; 1,1,1-Trifluoro-3-(2-furyl)-2-propanamine; 2-Propanamine, 1,1,1-trifluoro-3-(2-furanyl)-; α-(Trifluoromethyl)-2-furanmethanamine; Furan-2-yl-trifluoromethyl-ethylamine; TFPA
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-3-(Furan-2-Yl)Propan-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.