Description

[4-(4-Fluorophenyl)-1H-Pyrazol-1-Yl]Acetic Acid is a high-purity, functionalized heterocyclic acetic acid derivative, serving as a critical pharmaceutical intermediate and organic building block. Its molecular structure, featuring a fluorinated phenyl ring linked to a pyrazole-acetic acid core, makes it invaluable for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing targeted therapies and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the bioactivity of the fluorophenyl-pyrazole moiety.
• Material Science Research: Serves as a precursor for functionalized polymers and liquid crystals due to its rigid aromatic structure and carboxylic acid handle.
• Organic Synthesis Reagent: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation & Probe Development: The carboxylic acid group allows for conjugation to biomolecules, useful in creating diagnostic probes and biochemical tools.

Basic Information

Product Name	[4-(4-Fluorophenyl)-1H-Pyrazol-1-Yl]Acetic Acid
CAS No.	1206997-40-1
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	2-[4-(4-Fluorophenyl)-1H-pyrazol-1-yl]acetic acid; (4-(4-Fluorophenyl)-1H-pyrazol-1-yl)acetic Acid; 4-(4-Fluorophenyl)-1H-pyrazole-1-acetic acid; 1H-Pyrazole-1-acetic acid, 4-(4-fluorophenyl)-; 4-(p-Fluorophenyl)-1H-pyrazol-1-ylacetic Acid; 4-(4-Fluorophenyl)pyrazole-1-acetic Acid; FPPAA; 1206997-40-1
EINECS	Contact for details

Quality Control

Our production of [4-(4-Fluorophenyl)-1H-Pyrazol-1-Yl]Acetic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency for research and scale-up. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.