Description

n-(4-Bromo-2-Cyanophenyl)-4-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromo, cyano, and fluoro substituents. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers focused on creating novel compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals due to its rigid, multi-substituted aromatic core.
• Organic Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) in academic and industrial research settings.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological pathways.

Basic Information

Product Name	n-(4-Bromo-2-Cyanophenyl)-4-Fluorobenzamide
CAS No.	1206676-82-5
Molecular Formula	C14H8BrFN2O
Molecular Weight	319.13 g/mol
Synonyms	4-Fluoro-N-(4-bromo-2-cyanophenyl)benzamide; 4'-Fluoro-4-bromo-2-cyanobenzanilide; 1206676-82-5; Benzamide, N-(4-bromo-2-cyanophenyl)-4-fluoro-; N-(4-Bromo-2-cyanophenyl)-4-fluorobenzamide; 4-Fluoro-N-(4-bromo-2-cyanophenyl)benzamide
EINECS	Contact for details

Quality Control

Our n-(4-Bromo-2-Cyanophenyl)-4-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.