Description

4-Ethoxy-3-(trifluoromethyl)phenylacetic acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound, offered at 97% purity, is a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique trifluoromethyl and ethoxy substitution pattern. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Material Science: Employed in the creation of specialty polymers and coatings with tailored surface properties and chemical resistance.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorination chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Ethoxy-3-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1206593-28-3
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	2-[4-Ethoxy-3-(trifluoromethyl)phenyl]acetic acid; 4-Ethoxy-α-(trifluoromethyl)benzeneacetic acid; 3-Trifluoromethyl-4-ethoxyphenylacetic acid; 4-Ethoxy-3-trifluoromethylphenylacetic acid; (4-Ethoxy-3-(trifluoromethyl)phenyl)acetic acid; 2-(4-Ethoxy-3-(trifluoromethyl)phenyl)acetic acid; 4-Ethoxy-3-trifluoromethylbenzeneacetic acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-(trifluoromethyl)phenylacetic acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure compliance with specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.