Description

4-Fluoro-3-(Trifluoromethoxy)Benzamide is a high-value fluorinated aromatic building block with significant utility in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups can improve lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and advanced materials requiring specific electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	4-Fluoro-3-(Trifluoromethoxy)Benzamide
CAS No.	1206593-25-0
Molecular Formula	C8H5F4NO2
Molecular Weight	223.13 g/mol
Synonyms	4-Fluoro-3-(trifluoromethoxy)benzamide; 3-Trifluoromethoxy-4-fluorobenzamide; 4-Fluoro-α,α,α-trifluoro-m-anisamide; Benzamide, 4-fluoro-3-(trifluoromethoxy)-; 1206593-25-0; 4-Fluoro-3-trifluoromethoxybenzamide; 4-Fluoro-3-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.