Description

4-(Trifluoromethoxy)Benzeneacetic Acid Ethyl Ester is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile intermediate, introducing the trifluoromethoxy group—a key moiety known to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty monomers or ligands used in developing advanced polymers, liquid crystals, or metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed as a tool compound or a tag for modifying biomolecules to study protein function and interaction.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzeneacetic Acid Ethyl Ester
CAS No.	1206550-93-7
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	Ethyl 2-[4-(Trifluoromethoxy)phenyl]acetate; Ethyl (4-Trifluoromethoxyphenyl)acetate; 2-(4-(Trifluoromethoxy)phenyl)acetic Acid Ethyl Ester; p-(Trifluoromethoxy)phenylacetic Acid Ethyl Ester; 4-(Trifluoromethoxy)benzeneacetic Acid Ethyl Ester; α-(4-Trifluoromethoxyphenyl)acetic Acid Ethyl Ester; Ethyl 4-(Trifluoromethoxy)benzeneacetate
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Benzeneacetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP (Good Manufacturing Practice) and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.