Description

4-(Trifluoromethyl)Pyrimidine-2-Carbonitrile is a high-value, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a nitrile functionality, makes it an indispensable intermediate for creating novel compounds with tailored properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics and specialty polymers.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(Trifluoromethyl)Pyrimidine-2-Carbonitrile
CAS No.	1206459-86-0
Molecular Formula	C6H2F3N3
Molecular Weight	173.10 g/mol
Synonyms	2-Cyano-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-2-pyrimidinecarbonitrile; 4-(Trifluoromethyl)pyrimidine-2-carbonitrile; Pyrimidine-2-carbonitrile, 4-(trifluoromethyl)-; 1206459-86-0; 4-Trifluoromethylpyrimidine-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)Pyrimidine-2-Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and GC-MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.