Description

3-Azetidinecarbonitrile, 3-Ethyl-, Hydrochloride (1:1) is a high-purity, specialized heterocyclic building block used in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly in the construction of novel nitrogen-containing scaffolds for drug discovery. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel azetidine-based drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new chemical space.
• Agrochemical Development: Serves as a building block for creating new crop protection agents with unique modes of action.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological pathways and enzyme inhibition.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3-Azetidinecarbonitrile, 3-Ethyl-, Hydrochloride (1:1)
CAS No.	1205750-03-3
Molecular Formula	C6H10N2·HCl
Molecular Weight	146.62 g/mol
Synonyms	3-Ethyl-3-azetidinecarbonitrile hydrochloride; 3-Ethylazetidine-3-carbonitrile hydrochloride; 1-Azabicyclo[1.1.0]butane-3-carbonitrile, 3-ethyl-, hydrochloride; 3-Cyano-3-ethylazetidine hydrochloride; (3-Ethylazetidin-3-yl)carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Ethyl-3-azetidinecarbonitrile hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.