Description

4-Ethyl-4-Piperidinecarbonitrile Hydrochloride is a high-purity, versatile pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex molecules, offering a key nitrile-functionalized piperidine scaffold for medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthetic routes for potential APIs.
• Chemical Synthesis: Utilized in organic synthesis for introducing the 4-ethyl-4-cyanopiperidine moiety into more complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers and advanced materials.

Basic Information

Product Name	4-Ethyl-4-Piperidinecarbonitrile Hydrochloride
CAS No.	1205748-66-8
Molecular Formula	C8H14N2·HCl
Molecular Weight	174.67 g/mol
Synonyms	4-Cyano-4-ethylpiperidine hydrochloride; 4-Ethylpiperidine-4-carbonitrile hydrochloride; 4-Ethyl-4-cyanopiperidine hydrochloride; 4-Piperidinecarbonitrile, 4-ethyl-, hydrochloride; 1-(4-Ethyl-4-cyanopiperidin-1-yl)ethanone hydrochloride (common misnomer); 4-Ethyl-4-piperidinecarbonitrile HCl; 4-Ethyl-4-piperidine nitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Ethyl-4-Piperidinecarbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.