Description

1-Cyclopropoxy-4-Fluoro-Benzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the cyclopropoxy and fluoro substituents impart unique steric and electronic properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the metabolic stability often conferred by the fluorinated aromatic ring.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags used in biochemical assay development and diagnostic research.

Basic Information

Product Name	1-Cyclopropoxy-4-Fluoro-Benzene
CAS No.	1205501-33-2
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	4-Fluorophenyl cyclopropyl ether; p-Fluorophenyl cyclopropyl ether; Cyclopropyl 4-fluorophenyl ether; 1-Fluoro-4-(cyclopropyloxy)benzene; Benzene, 1-cyclopropoxy-4-fluoro-; 4-Cyclopropoxyfluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Cyclopropoxy-4-Fluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the material is stable at room temperature for shorter periods. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.