Description

(S)-3,3'-Bis(4-Chlorophenyl)-[1,1'-Binaphthalene]-2,2'-Diol CAS NO 1204609-08-4 is a high-purity, chiral binaphthol derivative, a crucial class of compounds in asymmetric synthesis. Its value lies in its role as a privileged ligand and catalyst precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance chiral auxiliaries.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metal complexes (e.g., with Ru, Rh, Pd) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
• Pharmaceutical Intermediate Synthesis: Critical for constructing the chiral backbone of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids, amines, or alcohols via diastereomeric salt formation or as a chiral stationary phase modifier.
• Organocatalysis: Acting as a chiral Brønsted acid catalyst in reactions such as Mannich, Friedel-Crafts, and Diels-Alder reactions.
• Material Science: A building block for chiral polymers, liquid crystals, and molecular recognition systems due to its rigid, helical structure.
• Agrochemical Research: Development of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(S)-3,3'-Bis(4-Chlorophenyl)-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1204609-08-4
Molecular Formula	C32H20Cl2O2
Molecular Weight	507.40 g/mol
Synonyms	(S)-3,3'-Bis(p-chlorophenyl)-1,1'-bi-2-naphthol; (S)-3,3'-Di(4-chlorophenyl)-BINOL; (S)-3,3'-Bis(4-chlorophenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (S)-3,3'-Bis(4-chlorophenyl)-1,1'-binaphthyl-2,2'-diol; (S)-3,3'-Bis(4-chlorophenyl)-BINOL; (S)-3,3'-Di-p-chlorophenyl-BINOL; (S)-Cl2-BINOL; (S)-3,3'-(4-Chlorophenyl)-BINOL
EINECS	Contact for details

Quality Control

Our (S)-3,3'-Bis(4-Chlorophenyl)-[1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, chiral HPLC assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.