Description

2-Formyl-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both an aldehyde and a boronic acid functional group on an electron-deficient aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and organic semiconductors, where its electron-withdrawing properties and ability to form conjugated systems are valuable.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that leverage boronic acid-diol interactions for detecting sugars or other biomolecules.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	2-Formyl-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1204580-94-8
Molecular Formula	C8H6BF3O3
Molecular Weight	217.94 g/mol
Synonyms	5-(Trifluoromethyl)-2-formylphenylboronic acid; 2-Formyl-5-(trifluoromethyl)benzeneboronic acid; (2-Formyl-5-(trifluoromethyl)phenyl)boronic acid; 2-Borono-5-(trifluoromethyl)benzaldehyde; Aldehyde-functionalized trifluoromethyl phenylboronic acid; Boronic acid pinacol ester precursor; Suzuki-Miyaura coupling reagent
EINECS	Contact for details

Quality Control

Every batch of 2-Formyl-5-(Trifluoromethyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality commitment aligns with the standards required for cGMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.