Description

2-Cyclopropylmethoxy-6-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern cross-coupling chemistry. Its core value lies in enabling the precise and efficient construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for Suzuki-Miyaura and other palladium-catalyzed coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in constructing biaryl and heterobiaryl scaffolds common in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the incorporation of fluorinated aromatic systems.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital component for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2-Cyclopropylmethoxy-6-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1204580-88-0
Molecular Formula	C₁₆H₂₂BFO₃
Molecular Weight	292.16 g/mol
Synonyms	2-(Cyclopropylmethoxy)-6-fluorophenylboronic acid pinacol ester; (2-(Cyclopropylmethoxy)-6-fluorophenyl)boronic acid pinacol ester; 6-Fluoro-2-(cyclopropylmethoxy)benzeneboronic acid pinacol ester; 2-Fluoro-6-(cyclopropylmethoxy)phenylboronic acid pinacol ester; B-[2-(Cyclopropylmethoxy)-6-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1204580-88-0; Boronic acid, B-[2-(cyclopropylmethoxy)-6-fluorophenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylmethoxy-6-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and pharmaceutical development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines, and specifications can be tailored to meet specific project requirements, including those for cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.