Description

1-Bromo-3-(1,1-Difluoropropyl)Benzene is a high-purity, specialized aromatic building block featuring both bromine and difluoropropyl functional groups. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the difluoropropyl group can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other advanced functional materials requiring specific halogenated and fluorinated components.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	1-Bromo-3-(1,1-Difluoropropyl)Benzene
CAS No.	1204295-68-0
Molecular Formula	C9H9BrF2
Molecular Weight	235.07 g/mol
Synonyms	3-Bromo-α,α-difluoropropylbenzene; 1-Bromo-3-(1,1-difluoropropyl)benzene; m-Bromo(1,1-difluoropropyl)benzene; Benzene, 1-bromo-3-(1,1-difluoropropyl)-; (3-Bromophenyl)(1,1-difluoropropyl); 3-(1,1-Difluoropropyl)phenyl bromide
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-3-(1,1-Difluoropropyl)Benzene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.