Description

4-Fluoro-3-(Methylsulfonyl)Phenylboronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a fundamental method for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, reliable intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aryl and heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and other fluorinated polymers.
• Chemical Biology & Probe Development: Employed in the construction of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds under mild conditions.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	4-Fluoro-3-(Methylsulfonyl)Phenylboronic Acid Pinacol Ester
CAS No.	1203655-90-6
Molecular Formula	C₁₃H₁₈BFO₄S
Molecular Weight	300.15 g/mol
Synonyms	4-Fluoro-3-(methylsulfonyl)benzeneboronic acid pinacol ester; 2-[4-Fluoro-3-(methylsulfonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Methylsulfonyl)-4-fluorophenylboronic acid pinacol ester; (4-Fluoro-3-methanesulfonylphenyl)boronic acid pinacol ester; Pinacol 4-Fluoro-3-(methylsulfonyl)benzeneboronate; B-[4-Fluoro-3-(methylsulfonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols to support our customers in pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.