Description

Brivaracetam-D7 is a deuterated analog of the antiepileptic drug Brivaracetam, specifically labeled with seven deuterium atoms. This compound is a critical stable isotope-labeled internal standard essential for ensuring the accuracy and reliability of quantitative bioanalytical methods. It is primarily used by pharmaceutical research laboratories and contract research organizations (CROs) engaged in drug metabolism and pharmacokinetics (DMPK) studies.

Application

• LC-MS/MS Internal Standard: Serves as a critical reference compound for the precise quantification of Brivaracetam in biological matrices (e.g., plasma, serum) during bioanalytical method development and validation.
• Pharmacokinetic (PK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Drug Metabolism Research: Used in metabolite identification and profiling studies to understand the biotransformation pathways of Brivaracetam.
• Therapeutic Drug Monitoring (TDM): Supports the development of robust assays for monitoring Brivaracetam concentrations in patient samples to optimize dosing regimens.
• Forensic and Clinical Toxicology: Facilitates the accurate detection and quantification of Brivaracetam in complex samples for diagnostic or legal purposes.
• Quality Control in Pharmaceutical Manufacturing: Can be utilized in analytical procedures to ensure the consistency and purity of Brivaracetam active pharmaceutical ingredient (API) and finished dosage forms.

Basic Information

Product Name	Brivaracetam-D7
CAS No.	1202896-51-2
Molecular Formula	C11H13D7N2O2
Molecular Weight	215.29 g/mol
Synonyms	(2S)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide-2,3,3,4,4,5,5-d7; Brivaracetam (D7, 98%); Brivaracetam-d7; UCB 34714-d7; (2S)-2-[(4R)-2-Oxo-4-propyl-1-pyrrolidinyl]butanamide-2,3,3,4,4,5,5-d7; Deuterated Brivaracetam; Brivaracetam Internal Standard
EINECS	Contact for details

Quality Control

Our Brivaracetam-D7 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay, isotopic enrichment, and impurity profile. We adhere to relevant industry standards for reference materials, and custom purity specifications are available to meet specific research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.