Description

2′-(Di-tert-Butylphosphino)Acetophenone Ethylene Ketal is a specialized, high-value organophosphorus ligand precursor used in advanced catalytic transformations. This compound matters for its role in constructing sophisticated chiral ligands, which are critical for enabling highly selective and efficient transition metal-catalyzed reactions in fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel synthetic routes and manufacturing complex molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the preparation of chiral phosphine ligands used in asymmetric hydrogenation and cross-coupling reactions to produce active pharmaceutical ingredients (APIs).
• Catalyst Development: Serves as a precursor for novel ligand systems in homogeneous catalysis, enabling more efficient and selective industrial chemical processes.
• Agrochemical Research: Used in the development of new, more effective, and environmentally friendly pesticides and herbicides through advanced catalytic methods.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value specialty chemicals where precise stereochemical control is required.
• Academic & Industrial R&D: A valuable reagent for exploring new methodologies in organic synthesis and organometallic chemistry within research laboratories.
• Material Science: Potential applications in the synthesis of functionalized polymers or advanced materials with tailored properties.

Basic Information

Product Name	2′-(Di-tert-Butylphosphino)Acetophenone Ethylene Ketal
CAS No.	1202864-99-0
Molecular Formula	C18H29O2P
Molecular Weight	308.40 g/mol
Synonyms	2-(Di-tert-butylphosphino)acetophenone ethylene ketal; 1-[2-(Di-tert-butylphosphino)phenyl]-2,2-dimethyl-1,3-dioxolane; Acetophenone, 2'-(bis(1,1-dimethylethyl)phosphino)-, ethylene ketal; 2'-(Bis(tert-butyl)phosphino)acetophenone ethylene ketal; 2-(Di-tert-butylphosphanyl)acetophenone ethylene ketal; (2,2-Dimethyl-1,3-dioxolan-4-yl)(2-(di-tert-butylphosphino)phenyl)methanone; Ligand precursor L*
EINECS	Contact for details

Quality Control

Our 2′-(Di-tert-Butylphosphino)Acetophenone Ethylene Ketal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ³¹P, ¹³C), and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity chemical intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain purity and efficacy. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
³¹P NMR Purity	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.