Description

Benzenemethanamine, 2-Fluoro-α,α,5-Trimethyl- is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fluorine substituent and a sterically hindered amine, makes it a valuable precursor for constructing complex molecules with tailored properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated characteristics.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	Benzenemethanamine, 2-Fluoro-α,α,5-Trimethyl-
CAS No.	1202853-63-1
Molecular Formula	C10H14FN
Molecular Weight	167.22 g/mol
Synonyms	2-Fluoro-α,α,5-trimethylbenzylamine; (2-Fluoro-5-methylphenyl)(1-methylethyl)methanamine; 1-(2-Fluoro-5-methylphenyl)-2-methylpropan-1-amine; α,α,5-Trimethyl-2-fluorobenzylamine; 2-Fluoro-α,α,5-trimethylbenzenemethanamine
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanamine, 2-Fluoro-α,α,5-Trimethyl- is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical synthesis workflows. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.