Description

trans-(4-(Trifluoromethyl)Cyclohexyl)Methanol is a high-purity fluorinated cyclohexyl derivative characterized by its unique trifluoromethyl group and trans-configuration. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, offering significant potential for modulating the physicochemical properties of target molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorine motifs for enhanced bioactivity, metabolic stability, or material performance.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Acts as a fluorinated component in the synthesis of advanced electronic materials for displays and organic light-emitting diodes (OLEDs), contributing to improved stability and performance.
• Polymer & Resin Modifier: Employed to introduce fluorine into polymer backbones or side chains, enhancing properties such as chemical resistance, thermal stability, and surface characteristics.
• Asymmetric Catalysis Ligand Precursor: Provides a rigid, fluorinated scaffold for the development of novel chiral ligands and catalysts used in enantioselective synthesis.
• Chemical Research & Development: A versatile building block for medicinal chemistry, process chemistry, and general organic synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	trans-(4-(Trifluoromethyl)Cyclohexyl)Methanol
CAS No.	1202577-61-4
Molecular Formula	C8H13F3O
Molecular Weight	182.18 g/mol
Synonyms	trans-4-(Trifluoromethyl)cyclohexanemethanol; (1r,4r)-4-(Trifluoromethyl)cyclohexylmethanol; (trans)-4-(Trifluoromethyl)cyclohexylmethanol; 4-(Trifluoromethyl)cyclohexanemethanol (trans-isomer); (1R,4R)-4-(Trifluoromethyl)cyclohexan-1-ylmethanol; 4-(Trifluoromethyl)cyclohexylcarbinol; 4-(Trifluoromethyl)cyclohexanemethanol, trans-; trans-4-(Trifluoromethyl)-1-cyclohexylmethanol
EINECS	Contact for details

Quality Control

Our trans-(4-(Trifluoromethyl)Cyclohexyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key specifications such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.