Description

2-(4-(Bromomethyl)Phenyl)-2-Methylpropanenitrile is a specialized organic building block featuring both a bromomethyl group and a nitrile functionality on a tertiary carbon center. This compound matters for its versatility as a key synthetic intermediate in constructing complex molecular architectures, particularly in pharmaceutical and advanced material research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and the development of novel polymers or liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a benzylic bromide moiety for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its reactive sites allow for the introduction of specific bioactive groups.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating advanced organic electronic materials due to its rigid phenyl core and modifiable functional groups.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functionalized resins, where the nitrile and bromide groups can initiate or participate in polymerization reactions.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes, affinity labels, or linker molecules for studying biological systems.

Basic Information

Item	Detail
Product Name	2-(4-(Bromomethyl)Phenyl)-2-Methylpropanenitrile
CAS No.	1201643-73-3
Molecular Formula	C11H12BrN
Molecular Weight	238.12 g/mol
Synonyms	2-[4-(Bromomethyl)phenyl]-2-methylpropanenitrile; α-(4-Bromobenzyl)isobutyronitrile; 2-Methyl-2-[4-(bromomethyl)phenyl]propanenitrile; 4-(2-Cyano-2-propyl)benzyl Bromide; p-(Bromomethyl)phenylisobutyronitrile; (4-Bromomethylphenyl)(cyano)dimethylmethane; 2-(4-Bromomethylphenyl)-2-methylpropionitrile
EINECS	Contact for details

Quality Control

Our 2-(4-(Bromomethyl)Phenyl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.