Description

(S)-2-Amino-3-Cyclobutylpropanoic Acid is a non-proteinogenic amino acid derivative featuring a cyclobutyl side chain, offering unique steric and conformational properties for advanced molecular design. This chiral building block is essential for medicinal chemistry research, enabling the development of novel peptide-based therapeutics and bioactive compounds. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers focused on creating constrained peptides, enzyme inhibitors, and other high-value synthetic targets.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of novel drug candidates, particularly protease inhibitors and receptor modulators.
• Constrained Peptide Design: Used to introduce conformational rigidity into peptide backbones, enhancing stability, potency, and metabolic resistance.
• Biochemical Research: Serves as a specialized substrate or inhibitor in enzymatic studies and structure-activity relationship (SAR) investigations.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in the preparation of enantiomerically pure compounds.
• Ligand Development: Useful for creating novel chelating agents or ligands for catalysis and molecular recognition applications.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry and medicinal chemistry for exploring new chemical space.

Basic Information

Product Name	(S)-2-Amino-3-Cyclobutylpropanoic Acid
CAS No.	1201593-65-8
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-2-Amino-3-cyclobutylpropionic acid; (S)-3-Cyclobutylalanine; (S)-Cyclobutylalanine; (S)-Hcyb(3); (S)-2-Amino-3-cyclobutylpropanoate; L-3-Cyclobutylalanine; (S)-α-Amino-cyclobutanepropanoic acid; (2S)-2-Amino-3-cyclobutylpropanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-Cyclobutylpropanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.