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Benzyl n-[1-({[(tert-Butoxy)Carbonyl]Amino}Methyl)Cyclopropyl]Carbamate CAS NO 1199792-80-7


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CAS No.:1199792-80-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzyl N-[1-({[(tert-Butoxy)Carbonyl]Amino}Methyl)Cyclopropyl]Carbamate is a sophisticated, high-purity chemical intermediate designed for advanced organic synthesis. This compound is critical for constructing complex molecular architectures, offering a protected amine functionality essential for peptide and small molecule drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, where precise chemical building blocks are paramount for success.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
  • Peptide Chemistry: Used for the introduction and protection of amino groups during solid-phase and solution-phase peptide synthesis.
  • Protecting Group Strategy: Serves as a reagent for the selective protection of primary amines, leveraging the Boc (tert-butoxycarbonyl) and Cbz (carboxybenzyl) protecting groups.
  • Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of compound libraries for high-throughput screening.
  • Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
  • Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted biopharmaceuticals.

Basic Information

Product Name Benzyl N-[1-({[(tert-Butoxy)Carbonyl]Amino}Methyl)Cyclopropyl]Carbamate
CAS No. 1199792-80-7
Molecular Formula C18H26N2O4
Molecular Weight 334.41 g/mol
Synonyms Benzyl (1-(((tert-butoxycarbonyl)amino)methyl)cyclopropyl)carbamate; 1-(((Boc-amino)methyl)cyclopropyl)carbamic acid benzyl ester; N-[(1-Aminomethylcyclopropyl)carbamoyloxy]benzyl tert-butylcarbamate; Boc-Cpr(Bn)-OH (common abbreviation); (1-(((tert-Butoxycarbonyl)amino)methyl)cyclopropyl)carbamic Acid Benzyl Ester; Benzyl N-(1-((((tert-butoxycarbonyl)amino)methyl)cyclopropyl)carbamate; BnOCO-Cpr(NHBoc)-H
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Quality Control

Our Benzyl N-[1-({[(tert-Butoxy)Carbonyl]Amino}Methyl)Cyclopropyl]Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Purity (HPLC, Area %) ≥ 99.0%
Single Impurity (HPLC) ≤ 0.5%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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