Description

Pyrrolidine-2-Carbonitrile Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrolidine or proline-like scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in drug discovery and lead optimization programs.
• Agrochemical Synthesis: Serves as an intermediate in the development of novel pesticides and herbicides with specific biological activity.
• Peptidomimetics Development: Employed in the design and synthesis of peptide analogs and conformationally restricted mimetics for biochemical studies.
• Catalyst and Ligand Preparation: Used in the preparation of chiral catalysts and ligands for asymmetric synthesis applications.
• Fine Chemical Production: A critical raw material for manufacturing specialty chemicals and advanced materials.

Basic Information

Product Name	Pyrrolidine-2-Carbonitrile Hydrochloride
CAS No.	1199773-80-2
Molecular Formula	C5H9N2·HCl
Molecular Weight	132.60 g/mol (Free base: 96.14 g/mol)
Synonyms	2-Cyanopyrrolidine Hydrochloride; Prolinenitrile Hydrochloride; (S)-Pyrrolidine-2-carbonitrile Hydrochloride (if applicable); 2-Pyrrolidinecarbonitrile Hydrochloride; 1-Azabicyclo[3.3.0]octane-2-carbonitrile Hydrochloride derivative; Pyrrolidine-2-carbonitrile HCl; 2-Cyano-pyrrolidine Hydrochloride
EINECS	Contact for details

Quality Control

Our Pyrrolidine-2-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.