Description

Fmoc-Orn(Ivdde)-Oh CAS NO 1198321-33-3 is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for constructing complex peptides with multiple reactive side chains, enabling precise control over sequential deprotection and coupling strategies. It is an essential building block for researchers and manufacturers in pharmaceutical development, proteomics, and the production of therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of complex peptide sequences, particularly those requiring orthogonal protection schemes.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based therapeutics, including hormone analogs, antimicrobial peptides, and targeted drug conjugates.
• Combinatorial Chemistry: Serves as a valuable building block in libraries for high-throughput screening to discover new bioactive compounds.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic, imaging, and therapeutic applications.
• Academic Research: Employed in universities and research institutes for studying protein structure-function relationships and developing new synthetic methodologies.

Basic Information

Product Name	Fmoc-Orn(Ivdde)-Oh
CAS No.	1198321-33-3
Molecular Formula	C₃₀H₃₇N₃O₇
Molecular Weight	551.63 g/mol
Synonyms	Fmoc-Orn(ivDde)-OH; N-α-Fmoc-N-δ-(ivDde)-L-ornithine; Fmoc-L-Orn(ivDde)-OH; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)pentanoic acid; N-α-(9-Fluorenylmethyloxycarbonyl)-N-δ-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)-L-ornithine; Fmoc-Ornithine(ivDde)-OH; Fmoc-Orn(ivDde)
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Orn(Ivdde)-Oh is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and chemical identity consistent with research and cGMP-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -15°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.