Description

cis-1-(Boc-Amino)-3-Cyanocyclohexane, 97% is a high-purity, protected amino nitrile building block essential for advanced organic synthesis. This compound matters because it provides a versatile chiral scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Peptidomimetic Chemistry: Serves as a constrained, non-natural amino acid analog for designing bioactive peptides and protease inhibitors.
• Agrochemical Research: Used in the development of new herbicides and pesticides with specific stereochemical requirements.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	cis-1-(Boc-Amino)-3-Cyanocyclohexane, 97%
CAS No.	1198163-56-2
Molecular Formula	C₁₂H₂₀N₂O₂
Molecular Weight	224.30 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)amino]-3-cyanocyclohexane (cis-); cis-1-(N-Boc-Amino)-3-cyanocyclohexane; cis-3-Cyano-1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexane; Boc-ACCH (cis-); tert-Butyl (cis-3-cyanocyclohexyl)carbamate; (1R,3S)-rel-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-cyclohexanecarbonitrile; (1S,3R)-rel-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-cyclohexanecarbonitrile
EINECS	Contact for details

Quality Control

Our cis-1-(Boc-Amino)-3-Cyanocyclohexane, 97% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the specified 97% minimum purity and consistent stereochemical integrity. Certificates of Analysis (COA) with full chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.