Description

1-{(1R,2S)-1-[(11Br)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]-1-Phenylpropan-2-Yl}-3-Phenylurea is a sophisticated chiral organophosphorus compound, serving as a high-value intermediate or ligand in advanced synthetic chemistry. Its precise stereochemistry and unique dinaphthodioxaphosphepin core make it a critical component for asymmetric catalysis and the synthesis of complex, biologically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, where it enables the development of novel therapeutics and specialty materials.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor in stereoselective transformations such as hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereocenters.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Material Science: Potential application in the synthesis of chiral polymers or advanced organic frameworks with specific optical properties.
• Academic & Process R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	1-{(1R,2S)-1-[(11Br)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]-1-Phenylpropan-2-Yl}-3-Phenylurea
CAS No.	1198080-55-5
Molecular Formula	C38H29BrNO4P
Molecular Weight	674.52 g/mol
Synonyms	(1R,2S)-1-[(11-Bromodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)oxy]-1-phenylpropan-2-yl 3-phenylurea; 1-[(1R,2S)-1-[(11-Bromodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)oxy]-1-phenylpropan-2-yl]-3-phenylurea; 1198080-55-5; (R,S)-Dinaphthodioxaphosphepin Urea Derivative; Bromo-Dinaphtho Dioxaphosphepin Urea Ligand; Chiral Phosphite-Urea Hybrid Ligand; CAS 1198080-55-5.
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral compound adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Quality is verified through advanced analytical techniques including HPLC, chiral analysis, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.