Description

Sulfamerazine-13C6 is a stable isotope-labeled analog of the sulfonamide antibiotic Sulfamerazine, where six carbon atoms are replaced with the carbon-13 isotope. This compound is essential as a high-purity internal standard for the accurate quantification of Sulfamerazine in complex matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in drug metabolism studies, pharmacokinetic research, and residue analysis to ensure data integrity and regulatory compliance.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical reference compound in Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) for the precise quantification of Sulfamerazine in biological samples.
• Pharmaceutical R&D: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of the parent drug.
• Veterinary Drug Residue Analysis: Enables accurate monitoring of Sulfamerazine residues in food-producing animals to ensure food safety and compliance with maximum residue limits (MRLs).
• Clinical Research: Supports bioanalytical method development and validation for clinical trials involving sulfonamide antibiotics.
• Environmental Testing: Applied in trace analysis of pharmaceutical pollutants in water and soil samples.
• Quality Control & Assurance: Used as a certified reference material (CRM) in pharmaceutical quality control laboratories to validate analytical methods.

Basic Information

Product Name	Sulfamerazine-13C6
CAS No.	1196157-80-8
Molecular Formula	C713C6H12N4O2S
Molecular Weight	278.30 (for 13C6 labeled form)
Synonyms	4-Amino-N-(4-methyl-2-pyrimidinyl-13C6)benzenesulfonamide; Sulfamerazine (13C6); 13C6-Sulfamerazine; [13C6]-Sulfamerazine; Sulfamerazine-13C6 Internal Standard; Isotopically Labeled Sulfamerazine; N1-(4-Methyl-2-pyrimidinyl-13C6)sulfanilamide
EINECS	Contact for details

Quality Control

Our Sulfamerazine-13C6 is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, which is critical for its role as an analytical standard. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity by HPLC, and identity confirmation. We adhere to relevant industry standards for reference materials to support GLP and GMP-compliant research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.