Description

2-Chloro-6-(Trifluoromethyl)Isonicotinonitrile CAS NO 1196155-38-0 is a high-value, multi-functional heterocyclic building block characterized by its chloro, trifluoromethyl, and nitrile substituents. This compound is engineered to serve as a critical intermediate in advanced synthetic chemistry, offering unique reactivity for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) specializing in complex, multi-step organic synthesis.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Isonicotinonitrile
CAS No.	1196155-38-0
Molecular Formula	C7H2ClF3N2
Molecular Weight	206.55 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)pyridine-4-carbonitrile; 4-Cyano-2-chloro-6-(trifluoromethyl)pyridine; 6-Chloro-2-(trifluoromethyl)isonicotinonitrile; 2-Chloro-6-trifluoromethyl-isonicotinonitrile; 2-Chloro-6-(trifluoromethyl)-4-pyridinecarbonitrile; 4-Pyridinecarbonitrile, 2-chloro-6-(trifluoromethyl)-; Isonicotinonitrile, 2-chloro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethyl)Isonicotinonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP (current Good Manufacturing Practice) synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.