Description

2-Trifluoromethyl-Morpholine Hydrochloride is a high-value fluorinated morpholine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl group imparts desirable properties such as enhanced metabolic stability and lipophilicity, making it indispensable for modern chemical research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the creation of novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for CNS and metabolic disease targets.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioactivity.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials requiring fluorinated components.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Fine Chemical Production: Serves as a versatile intermediate for custom synthesis and contract manufacturing projects.

Basic Information

Product Name	2-Trifluoromethyl-Morpholine Hydrochloride
CAS No.	1196152-51-8
Molecular Formula	C5H9ClF3NO
Molecular Weight	191.58 g/mol
Synonyms	2-(Trifluoromethyl)morpholine hydrochloride; 4-(Trifluoromethyl)morpholine HCl; Morpholine, 2-(trifluoromethyl)-, hydrochloride; 2-Trifluoromorpholine hydrochloride; 2-TFM-Morpholine HCl; 2-CF3-Morpholine Hydrochloride; 2-Trifluoromethyltetrahydro-1,4-oxazine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Morpholine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support custom synthesis to meet specific research-grade or GMP-starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.