Description

3-Fluoro-5-(Isopropoxy)Phenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in constructing advanced herbicide and fungicide molecules with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic display and lighting materials.
• Polymer Chemistry: Enables the creation of specialty polymers and functionalized materials with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boron-containing coupling partner with aryl/vinyl halides or triflates.

Basic Information

Product Name	3-Fluoro-5-(Isopropoxy)Phenylboronic Acid
CAS No.	1195945-65-3
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(3-Fluoro-5-isopropoxyphenyl)boronic acid; 3-Fluoro-5-isopropoxybenzeneboronic acid; 3-Fluoro-5-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-[3-fluoro-5-(1-methylethoxy)phenyl]-; 3-Fluoro-5-isopropoxy phenylboronic acid; 3-Fluoro-5-(propan-2-yloxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Isopropoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.