Description

β-Ureido-L-α-Tosylaminopropionic Acid is a specialized, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block for the development of novel pharmaceuticals and bioactive molecules, enabling precise control over stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, enzyme inhibitor development, and the synthesis of complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used to construct unnatural amino acid residues within peptide chains to enhance metabolic stability, bioavailability, and binding affinity of peptide-based drug candidates.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified compounds for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Medicinal Chemistry Libraries: Incorporated into compound libraries for high-throughput screening to identify new leads with potential therapeutic activity.

Basic Information

Product Name	β-Ureido-L-α-Tosylaminopropionic Acid
CAS No.	1195628-02-4
Molecular Formula	C11H15N3O5S
Molecular Weight	301.32 g/mol
Synonyms	(2S)-2-[[(4-Methylphenyl)sulfonyl]amino]-3-ureidopropanoic Acid; L-β-Ureidoalanine N-p-Tosyl Derivative; Nα-Tosyl-Nβ-ureido-L-diaminopropionic Acid; 3-Ureido-2-(p-toluenesulfonamido)propionic Acid; (S)-2-(Tosylamino)-3-ureidopropanoic Acid; β-Ureidoalanine Tosylamide; BOC Sciences Brand Name BLD-1195628
EINECS	Contact for details

Quality Control

Our β-Ureido-L-α-Tosylaminopropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA) providing purity, chiral excess, and impurity profiles is supplied with every order to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.