Description

(2S)-3-(Carbamoylamino)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid is a sophisticated, high-purity Fmoc-protected amino acid derivative designed for advanced synthetic applications. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptides and bioconjugates. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality intermediates for creating novel therapeutic agents and functional biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential assembly of peptide chains on resin supports.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including potential treatments for metabolic, oncological, and neurological disorders.
• Bioconjugation: Facilitates the site-specific attachment of peptides to proteins, antibodies, or other macromolecules for diagnostic and therapeutic applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Proteomics and Biochemical Research: A tool for synthesizing custom peptide substrates, inhibitors, or probes for enzyme studies and signal transduction pathway analysis.
• Material Science: Used in the development of peptide-based biomaterials, hydrogels, and surface coatings with specific biological functionalities.

Basic Information

Product Name	(2S)-3-(Carbamoylamino)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid
CAS No.	1192601-91-4
Molecular Formula	C19H19N3O5
Molecular Weight	369.37 g/mol
Synonyms	Fmoc-Asn-OH; Nα-Fmoc-L-asparagine; Fmoc-L-Asparagine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-asparagine; (2S)-2-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-3-carbamoylpropanoic acid; Fmoc-NH-OH; Fmoc-Asparagine; L-Asparagine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Every batch of our (2S)-3-(Carbamoylamino)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications, including peptide synthesis. Certificates of Analysis (COA) detailing purity, chiral integrity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere or with desiccant and opened only in a moisture-controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	-10.0° to -15.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.