Description

n-Boc-Hept-6-Yn-1-Amine is a protected amine building block featuring a terminal alkyne functional group, making it a versatile intermediate in organic synthesis. Its core value lies in enabling the controlled introduction of amine functionality into complex molecular architectures via click chemistry and peptide coupling strategies. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry for creating amide and urea derivatives.
• Peptide Mimetics & PROTACs: Used in the construction of peptide backbones and as a linker component in Proteolysis Targeting Chimeras (PROTACs) due to its orthogonal protecting group.
• Click Chemistry Substrate: The terminal alkyne allows for efficient Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition) to create triazole linkages.
• Agrochemical Synthesis: Intermediate in the production of specialized herbicides, fungicides, and plant growth regulators requiring specific amine-alkyne motifs.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating advanced polymers with tailored properties.
• Bioconjugation: Facilitates the site-specific labeling of proteins, antibodies, and other biomolecules for diagnostic and research applications.

Basic Information

Product Name	n-Boc-Hept-6-Yn-1-Amine
CAS No.	1192373-48-0
Molecular Formula	C₁₂H₂₁NO₂
Molecular Weight	211.30 g/mol
Synonyms	1-Heptyn-7-amine, N-BOC-; tert-Butyl (7-aminohept-1-yn-1-yl)carbamate; N-(tert-Butoxycarbonyl)-6-heptyn-1-amine; Boc-6-heptyn-1-amine; 6-Heptyn-1-amine, N-BOC-protected; BocNH-(CH₂)₅-C≡CH; N-Boc-6-heptyn-1-amine; 7-Amino-1-heptyne, N-Boc derivative
EINECS	Contact for details

Quality Control

Our n-Boc-Hept-6-Yn-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider using a desiccator or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.