Description

2-(2-Fluoro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis. CAS No. 1192045-84-3.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially fluorinated compounds.
• Agrochemical Synthesis: Used to create advanced, targeted pesticides and herbicides by introducing the specific fluorinated phenyl moiety into complex molecules.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	2-(2-Fluoro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1192045-84-3
Molecular Formula	C₁₃H₁₈BFO₂
Molecular Weight	236.09 g/mol
Synonyms	2-Fluoro-5-methylbenzeneboronic acid pinacol ester; (2-Fluoro-5-methylphenyl)boronic acid pinacol ester; 2-(2-Fluoro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Fluoro-5-methylphenylboronic acid pinacol ester; 2-Fluoro-5-methylphenyl-Bpin; Pinacol (2-fluoro-5-methylphenyl)boronate; 1192045-84-3; 2-Fluoro-5-methylbenzeneboronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.