Description

(R)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a high-value, chiral organophosphorus compound that serves as a sophisticated ligand or catalyst precursor in asymmetric synthesis. Its precise stereochemistry and unique binaphthyl backbone make it indispensable for achieving high enantioselectivity in critical chemical transformations. This advanced intermediate is primarily sought by research and development teams in the pharmaceutical and fine chemical industries, where it is used to create novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor for enantioselective hydrogenation, carbon-carbon bond formation, and other transition metal-catalyzed reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of complex, chiral drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Material Science Research: Utilized in the development of chiral polymers, liquid crystals, and other advanced functional materials with specific optical properties.
• Methodology Development: Employed by academic and industrial research laboratories to develop new catalytic systems and synthetic methodologies.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for commercial pharmaceutical production under GMP conditions.

Basic Information

Item	Details
Product Name	(R)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1191451-24-7
Molecular Formula	C44H24Cl4O4P2
Molecular Weight	828.42 g/mol
Synonyms	(R)-3,3'-Bis(3,5-dichlorophenyl)-1,1'-binaphthalene-2,2'-diyl hydrogen phosphate; (R)-BINOL-Derived Phosphoric Acid; (R)-3,3'-Bis(3,5-dichlorophenyl)-BINOL Phosphoric Acid; (R)-TRIP Analogue; Chiral Phosphoric Acid Ligand; (R)-BINOL-3,3'-di(3,5-dichlorophenyl) hydrogenphosphate; Asymmetric Organocatalyst; (R)-BINOL-DCPP
EINECS	Contact for details

Quality Control

Every batch of (R)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is produced and tested under stringent quality management systems. We ensure compliance with the highest purity standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect performance. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.