Description

(11Br)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1′,2′-E]Phosphepine is a specialized organophosphorus compound featuring a unique dinaphthophosphepine scaffold. This compound is of significant value as a key chiral ligand or precursor in asymmetric catalysis, enabling the synthesis of high-value, enantiomerically pure intermediates. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents and advanced materials.

Application

• Asymmetric Catalysis: Serves as a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: A critical building block for constructing complex, stereodefined molecular architectures in drug discovery.
• Advanced Material Research: Used in the development of novel organic electronic materials and chiral polymers.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic and organometallic chemistry.
• Precursor for Functionalized Ligands: The bromine substituent allows for further derivatization to create custom-tailored ligand libraries.

Basic Information

Item	Details
Product Name	(11Br)-4,5-Dihydro-3H-Dinaphtho[2,1-C:1′,2′-E]Phosphepine
CAS No.	1191447-90-1
Molecular Formula	C23H16BrP
Molecular Weight	403.25 g/mol
Synonyms	11-Bromo-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepine; (11-Bromodinaphthophosphepine); Dinaphtho[2,1-c:1',2'-e]phosphepine, 11-bromo-4,5-dihydro-3H-; Bromo-DNPP; Br-DNPP; Chiral dinaphthophosphepine ligand; Asymmetric phosphine ligand
EINECS	Contact for details

Quality Control

Our (11Br)-4,5-Dihydro-3H-Dinaphthophosphepine is produced under stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive catalytic applications. Each lot is characterized by NMR (¹H, ³¹P, ¹³C), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The compound is easily oxidized and moisture-sensitive; ensure the container is sealed immediately after use and stored in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.