Description

2,3-Difluorophenylboronic Acid n-Butyldiethanolamine Ester is a specialized organoboron compound, specifically a protected boronic acid ester. This chemical matters as a crucial synthetic intermediate, offering enhanced stability and solubility for advanced cross-coupling reactions, particularly in Suzuki-Miyaura couplings. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex fluorinated aromatic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing a 2,3-difluorophenyl moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides with fluorinated aromatic systems.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling Reactions: A stable, protected reagent for palladium-catalyzed carbon-carbon bond formation under various reaction conditions.
• Ligand and Catalyst Development: Utilized in the preparation of novel boron-containing ligands for catalytic systems.
• Chemical Biology Probes: Employed in the synthesis of fluorinated molecules for studying biological processes and target engagement.

Basic Information

Product Name	2,3-Difluorophenylboronic Acid n-Butyldiethanolamine Ester
CAS No.	1190989-00-4
Molecular Formula	C₁₄H₂₀BF₂NO₂
Molecular Weight	283.12 g/mol
Synonyms	2,3-Difluorophenylboronic Acid N-Butyldiethanolamine Ester; B-(2,3-Difluorophenyl)-N-butyl-2,2'-iminodiethanolboronate; N-Butyldiethanolamine 2,3-Difluorophenylboronate; 2,3-Difluorophenylboronic Acid Diethanolamine Butyl Ester; Boronic acid, B-(2,3-difluorophenyl)-, compd. with N-butyldiethanolamine (1:1); 1190989-00-4; 2,3-DFPBA-BDEA Ester
EINECS	Contact for details

Quality Control

Our 2,3-Difluorophenylboronic Acid n-Butyldiethanolamine Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.