Description

1-(6-Chloro-2-Pyridinyl)-Cyclobutanecarbonitrile is a specialized organic compound featuring a cyclobutane ring fused with a chlorinated pyridine moiety. This unique structure makes it a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients. The compound's utility lies in its role as a key building block for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective drug candidates.
• Agrochemical Research: Serves as a key building block for developing new pesticides, herbicides, or fungicides, leveraging the bioactivity of the pyridine and nitrile groups.
• Chemical Synthesis: Used in organic chemistry research for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Material Science: Potential intermediate for the development of specialty polymers or ligands for catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for the life sciences industry.

Basic Information

Product Name	1-(6-Chloro-2-Pyridinyl)-Cyclobutanecarbonitrile
CAS No.	1190644-32-6
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	1-(6-Chloro-2-pyridinyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(6-chloro-2-pyridinyl)-; 1-(6-Chloropyridin-2-yl)cyclobutanecarbonitrile; 6-Chloro-2-(1-cyanocyclobutyl)pyridine; 2-(1-Cyanocyclobutyl)-6-chloropyridine; 1-(6-Chloro-2-pyridyl)cyclobutanecarbonitrile; 1190644-32-6
EINECS	Contact for details

Quality Control

Our production of 1-(6-Chloro-2-Pyridinyl)-Cyclobutanecarbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality systems are designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.