Description

1-{[4-(4-Methoxyphenyl)-1,2,3-Thiadiazol-5-Yl]Carbonyl}Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• API Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales for new pharmaceuticals.
• Biochemical Tool Compound: May be utilized in vitro to study specific enzyme inhibition or receptor modulation due to its distinctive thiadiazole and piperidine motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client R&D programs.

Basic Information

Product Name	1-{[4-(4-Methoxyphenyl)-1,2,3-Thiadiazol-5-Yl]Carbonyl}Piperidine-4-Carboxamide
CAS No.	1190259-34-7
Molecular Formula	C16H18N4O3S
Molecular Weight	346.40 g/mol
Synonyms	1-[(4-(4-Methoxyphenyl)-1,2,3-thiadiazol-5-yl)carbonyl]piperidine-4-carboxamide; 4-Carbamoyl-1-[[4-(4-methoxyphenyl)-1,2,3-thiadiazol-5-yl]carbonyl]piperidine; Piperidine-4-carboxamide, 1-[[4-(4-methoxyphenyl)-1,2,3-thiadiazol-5-yl]carbonyl]-; 1190259-34-7; 4-(4-Methoxyphenyl)-1,2,3-thiadiazole-5-carboxylic acid piperidin-4-ylamide; 1-({4-[4-(Methyloxy)phenyl]-1,2,3-thiadiazol-5-yl}carbonyl)-4-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our production of 1-{[4-(4-Methoxyphenyl)-1,2,3-Thiadiazol-5-Yl]Carbonyl}Piperidine-4-Carboxamide adheres to stringent quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.