Description

Fasinumab CAS NO 1190239-42-9 is a high-purity, investigational monoclonal antibody designed to selectively target nerve growth factor (NGF). This compound is critical for advanced research and development in the field of chronic pain management, offering a targeted mechanism of action. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on developing next-generation analgesics for conditions such as osteoarthritis and chronic lower back pain.

Application

• Pharmaceutical Research & Development (R&D): Primary application in preclinical and clinical studies for novel pain therapeutics.
• Biologics Manufacturing: Serves as a reference standard or key intermediate in the production of monoclonal antibody-based drugs.
• Mechanistic Studies: Used in laboratory settings to investigate the NGF signaling pathway and its role in nociception and inflammation.
• Assay Development: Essential for creating and validating bioanalytical methods (e.g., ELISA, cell-based assays) for pharmacokinetic and pharmacodynamic studies.
• Academic Research: Employed in university and institutional labs for basic science research into neurobiology and chronic pain models.

Basic Information

Product Name	Fasinumab
CAS No.	1190239-42-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	REGN 475; SAR 164877; Anti-NGF Monoclonal Antibody REGN475; Anti-Nerve Growth Factor Antibody; Tanezumab Analog; Fasinumab (INN); Fasinumab (USAN); Fully Human Anti-NGF Monoclonal Antibody
EINECS	Contact for details

Quality Control

Our Fasinumab is manufactured under strict quality systems to ensure the highest standards of purity and consistency, suitable for research and development use. Each batch is supported by a comprehensive Certificate of Analysis (COA) that includes data on purity, potency, and biological activity. We adhere to relevant GMP guidelines for the production of biopharmaceutical intermediates, ensuring traceability and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under controlled humidity conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Purity (SDS-PAGE / SEC-HPLC)	≥ 95%
Protein Content (UV Absorbance)	As per COA
Biological Activity (Cell-based Assay)	As per COA
Endotoxin Level (LAL Test)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile
Identification (Mass Spectrometry)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.