Description

Carebastine-D5 Methyl Ester is a deuterated analog of a key pharmaceutical intermediate, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry and other advanced analytical techniques. It is primarily utilized by research institutions, pharmaceutical developers, and contract research organizations (CROs) engaged in pharmacokinetic studies, drug metabolism research, and quality control for active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Carebastine and related metabolites in biological matrices during bioanalytical studies.
• Pharmaceutical R&D: Used in method development and validation for drug metabolism and pharmacokinetics (DMPK) research.
• Metabolite Tracing: Serves as a stable isotope-labeled tracer in metabolic pathway studies and impurity profiling.
• Quality Assurance/Control: Employed in GMP and non-GMP analytical laboratories to ensure the accuracy of assay results for pharmaceutical compounds.
• Reference Standard: Acts as a certified reference material for calibrating analytical instruments and verifying method performance.

Basic Information

Product Name	Carebastine-D5 Methyl Ester
CAS No.	1190019-51-2
Molecular Formula	C26H30D5N3O3
Molecular Weight	Contact for details
Synonyms	Carebastine-d5 Methyl Ester; Methyl 8-fluoro-5-[(1H-1,2,4-triazol-1-yl)methyl]-1-[2-([(2H5)phenyl]methoxy)ethyl]-1,3-dihydro-2H-1,4-benzodiazepin-2-one-2,3,4,5,6-d5; Deuterated Carebastine Methyl Ester; Carebastine (methyl ester-d5); 1,4-Benzodiazepin-2-one, 8-fluoro-5-[(1H-1,2,4-triazol-1-yl)methyl]-1-[2-([(2,3,4,5,6-2H5)phenyl]methoxy)ethyl]-1,3-dihydro-, methyl ester
EINECS	Contact for details

Quality Control

Our Carebastine-D5 Methyl Ester is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry guidelines to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.