Description

α-Carboline-15N2 is a stable isotope-labeled analog of the α-carboline alkaloid, where two nitrogen atoms are enriched with the 15N isotope. This compound is essential for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway elucidation using mass spectrometry. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and life science sectors for drug discovery, pharmacokinetic studies, and biochemical tracer applications.

Application

• Internal standard for the quantitative analysis of α-carboline and related alkaloids via LC-MS and GC-MS.
• Tracer compound in drug metabolism and pharmacokinetics (DMPK) studies to investigate absorption, distribution, metabolism, and excretion (ADME).
• Biochemical research tool for studying enzyme mechanisms and metabolic pathways involving nitrogen-containing heterocycles.
• Precursor in the synthesis of isotopically labeled complex molecules for pharmaceutical research and development.
• Reference material for method development and validation in analytical laboratories to ensure accuracy and regulatory compliance.
• Use in environmental fate studies to track the degradation and transformation of carboline-based compounds.

Basic Information

Product Name	α-Carboline-15N2
CAS No.	1189983-12-7
Molecular Formula	C11H815N2
Molecular Weight	170.20 g/mol (approx.)
Synonyms	9H-Pyrido[2,3-b]indole-15N2; 1-Aza-9H-β-carboline-15N2; α-Carboline-15N2; Norharmane-15N2; 9H-Pyrido[3,4-b]indole-15N2; Isotopically Labeled α-Carboline; [15N2]-α-Carboline
EINECS	Contact for details

Quality Control

Our α-Carboline-15N2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry, to confirm isotopic enrichment, chemical purity, and identity. A detailed Certificate of Analysis (COA) is provided, documenting the assay, isotopic purity, and any relevant impurities. We ensure compliance with the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (15N)	≥ 98 atom % 15N
Isotopic Enrichment	≥ 99% on two labeled positions
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.